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  6. Thermo Scientific Chemicals 2'-Deoxyuridine, 98+%, Thermo Scientific Chemicals

Thermo Scientific Chemicals 2'-Deoxyuridine, 98+%, Thermo Scientific Chemicals

Codice prodotto. 11478656
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Quantità:
1 g
5 g
25 g
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2?-deoxyuridine include 5-ethynyl-2?-deoxyuridine (DdU) and 5-hydroxymethyl-2?-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2′-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-Deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.

Solubility
Soluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 951-78-0
Formula molecolare C9H12N2O5
Molecular Weight (g/mol) 228.20
Numero MDL MFCD00006527
InChI Key MXHRCPNRJAMMIM-SHYZEUOFSA-N
Sinonimo 2'-deoxyuridine, deoxyuridine, uracil deoxyriboside, 2-deoxyuridine, 1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidine-2,4 1h,3h-dione, deoxyribose uracil, uridine, 2'-deoxy, 2'-desoxyuridine, unii-w78i7ay22c, ccris 2832
PubChem CID 13712
ChEBI CHEBI:16450
IUPAC Name 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O

Specifica

Materiale o nome chimico 2'-Deoxyuridine
Punto di fusione 164°C to 167°C
Quantità 1 g
Beilstein 24433
Sensibilità Air Sensitive
Indice di Merck 14,2910
Informazioni di solubilità Soluble in water.
Optical Rotation +52° (c=1.1 in 1N NaOH)
Peso formulazione 228.21
Percent Purity 99%

RUO – Research Use Only

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