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  6. Thermo Scientific Chemicals Anhydrotetracycline hydrochloride, 'can be used as a secondary standard'

Thermo Scientific Chemicals Anhydrotetracycline hydrochloride, 'can be used as a secondary standard'

Codice prodotto. 10792081
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Quantità:
100 mg
500 mg
Imballaggio:
Bottiglia in vetro
Glass bottle
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Descrizione

Anhydrotetracycline hydrochloride, CAS # 13803-65-1, is a tetracycline derivative showing antibacterial activity commonly used to control tetracycline-dependent gene expression systems in bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Anhydrotetracycline hydrochloride is a degradation product derived from tetracycline hydrochloride. It acts as an effector of tetracycline-dependent gene expression in bacterial expression systems. In this system the transcription of genes is reversibly turned on/off in the presence of several compounds including, anhydrotetracycline hydrochloride.
  • This compound poorly binds to the 30S ribosomal subunit compared with its precursor, tetracycline.

Applications

  • Anhydrotetracycline hydrochloride is commonly used in all fields of biology for control of transcription or translation processes
  • This compound has been used in laboratory experiments and shows lower antibacterial activity against Escherichia coli compared with tetracycline.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 13803-65-1
Formula molecolare C22H23ClN2O6
Molecular Weight (g/mol) 446.88
Numero MDL MFCD00151453
InChI Key FFZXKJVSZDKEMY-XGRJIHFXNA-N
Sinonimo anhydrotetracycline hydrochloride, unii-ovg14h105r, anhydrotetracycline hcl, c22h22n2o7.hcl, 2-naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, 4s-4alpha,4aalpha,12aalpha, 4-dimethylamino-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride, 4s-4alpha,4aalpha,12aalpha, anhydrotetracycline hydrochloride, vetranal tm , analytical standard, anhydrotetracycline hydrochloride, certified reference material, tracecert r, anhydrotetracycline hydrochloride, european pharmacopoeia ep reference standard, anhydrotetracycline hydrochloride, united states pharmacopeia usp reference standard
PubChem CID 54710409
IUPAC Name (4S,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride
SMILES [H+].[Cl-].CN(C)C1C2CC3=C(C(O)=C4C=CC=CC4=C3C)C(=O)C2(O)C(=O)\C(=C(\N)O)C1=O

Specifica

Materiale o nome chimico Anhydrotetracycline hydrochloride
Punto di fusione 223.0°C
Colore Giallo
Spettro a infrarossi Authentic
Intervallo percentuale saggio 80% min. (as is,calculated)
Imballaggio Bottiglia in vetro
Quantità 100 mg
Beilstein 14, IV, 2633
Rotazione specifica − 264.00
Informazioni di solubilità Solubility in water: 5g/L. Other solubilities: 50g/L methanol
Peso formulazione 462.89
Percent Purity ≥97.0% (on anhydrous substance), ≥80 wt% (as is, calculated)(HPLC)
Forma fisica In polvere
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Sicurezza e movimentazione

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Identificativo prodotto
  • Anhydrotetracycline hydrochloride
 Avvertenza
  • Attenzione
 Categoria di pericolo
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Tossicità per la riproduzione Categoria 2
 Indicazioni di pericolo
  • H361d-Sospettato di nuocere al feto.
  • H319-Provoca grave irritazione oculare.
 Consigli di prudenza
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

RUO – Research Use Only

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