CEACAM8 Mouse anti-Human, Clone: GM2H6, Invitrogen™

Descrizione

This antibody recognizes native human CEACAM8 protein expressed in transfected mammalian cells.

CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a MW of 95kDa which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains.