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Tocris Bioscience™ CHDI 00484077
Potent and selective HDAC class IIa inhibitor
Marca: Tocris Bioscience™ 7879/5
Dettagli aggiuntivi : Peso : 0.00970kg
Descrizione
CHDI 00484077 is a potent and selective class IIa histone deacetylase HDAC inhibitor (IC50 values = 10-30 nM in vivo, 0.01 nM and 0.04 nM in HEK293 and Jurkat cells, respectively). Exhibits 150-fold selectivity for class IIa over class I/IIb HDACs in cells. Orally bioavailable and CNS penetrant.Specifica
N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide | |
Class II Histone Deacetylases Inhibitors | |
98% |
5 mg | |
C18H21F3N4O2 |