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Epidermal Growth Factor Receptor/EGFR Ab-5 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, immunoprecipitation and flow cytometry experiments.
Marca: Epredia MS-316-PABX
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Descrizione
EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Host Species: Mouse
Clone: H11
Isotype: IgG1/κ
Species Reactivity: Human. Does not react with mouse and rat. Others not known.
Epitope: Extracellular domain
Immunogen: HC2 20 d2 cells
Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)
Positive Control: A431 cells, Placenta or Squamous cell CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native only)
- Flow Cytometry
Note:
USA: RUO; Int'l: RUO
Specifica
| Epidermal Growth Factor Receptor/EGFR Ab-5 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| EGFR Family | |
| Human | |
| IgG1 κ |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| H11 | |
| Unconjugated | |
| HC2 20 d2 cells | |
| RUO | |
| Primary | |
| Concentrated |
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