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Glibenclamide, Tocris Bioscience™

Codice prodotto. 18772574
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Quantità:
100 mg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Kir6 (KATP) channel blocker

ATP-dependent K+ channel (Kir6, KATP) and CFTR Cl- channel blocker. Inhibits Kir6 currents in the pancreas, causing an increase in intracellular Ca2+ and insulin secretion. Inhibits recombinant CFTR Cl- channels with an IC50 of 20 μM.

Specifica

Materiale o nome chimico Glibenclamide
CAS 10238-21-8
Formula molecolare C23H28ClN3O5S
Quantità 100 mg
Sinonimo glyburide, glibenclamide, glybenclamide, micronase, diabeta, glynase, daonil, euglucon, maninil, semi-daonil
InChI Key ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
IUPAC Name 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Molecular Weight (g/mol) 494.003
PubChem CID 3488
ChEBI CHEBI:5441
Peso formulazione 494
Percent Purity >99%
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