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GRP94 Mouse anti-Human, Mouse, Rat, Clone: 1H10B7, Proteintech
Mouse Monoclonal Antibody
121.38€ - 325.38€
Specifica
Antigene | GRP94 |
---|---|
Clone | 1H10B7 |
Concentrazione | 1 mg/mL |
Applicazioni | Immunocytochemistry, Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin) |
Classificazione | Monoclonal |
Descrizione
This antibody was generated against the N-terminal region of full-length HSP90b1.
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.Specifica
GRP94 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
ECGP, GP96, GRP 94, GRP94, HSP90B1, TRA1, Tumor rejection antigen 1 | |
Hsp90b1 | |
IgM | |
Caprylic Acid Precipitation | |
Antibody |
1H10B7 | |
Immunocytochemistry, Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin) | |
Unconjugated | |
Mouse | |
Rat, Mouse, Human | |
P08113, P14625, Q66HD0 | |
22027, 362862, 7184 | |
GRP94 Fusion Protein Ag1439 | |
Primary | |
-20°C | |
HSP90B1 |