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  7. Thermo Scientific Chemicals Indomethacin

Thermo Scientific Chemicals Indomethacin

Catalog Number 15462202
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Quantità:
5 g
100 g
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
53-86-1
C19H16ClNO4
357.79
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
53-86-1
C19H16ClNO4
357.79
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Descrizione

Indomethacin, CAS # 53-86-1, is an indole-based nonsteroidal anti-inflammatory (NSAID).

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Indomethacin is a synthetic NSAID of the indole family that inhibits cyclooxygenase and reduces prostaglandin and pyrogen release

• Indomethacin may suppress the multi-drug resistant transporter and thereby increase the efficacy of antineoplastics

• Indomethacin activates phosphatases that inhibit signaling pathways associated with cancer cell migration and proliferation

Applications

• Indomethacin may be used for the laboratory study of cancer cell proliferation, tumorigenesis and drug interactions

• Indomethacin may be used for laboratory study of the effect of inhibiting the multi-drug resistance transporter, or for downregulation of survival signaling in cells via survivin

TRUSTED_SUSTAINABILITY
Materiale o nome chimico Indomethacin
Punto di fusione 155.0°C
Perdita all'essiccatura 0.5% max. (100°C, 2 h, 5 mm Hg)
Spettro a infrarossi Authentic
Quantità 5 g
Peso formulazione 357.79
Percent Purity ≥97.5% (HPLC)

Sicurezza e movimentazione

compliance-icons compliance-icons
Identificativo prodotto
  • Indomethacin
 Avvertenza
  • Pericolo
 Categoria di pericolo
  • Tossicità acuta Categoria 1
  • Sensibilizzazione della pelle Categoria 1
  • Tossicità per la riproduzione Categoria 1B
 Indicazioni di pericolo
  • H300-Letale se ingerito.
  • H317-Può provocare una reazione allergica cutanea.
  • H360FD-Può nuocere alla fertilità. Può nuocere al feto.
 Consigli di prudenza
  • P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico/
  • P330-Sciacquare la bocca.
  • P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/sapone.
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.

RUO – Research Use Only

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