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  6. 30001470

Jasplakinolide, Tocris Bioscience™

Codice prodotto. 30001470
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Quantità:
100 μg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Stabilizes F-actin; promotes actin polymerization

Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ∽ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.

Specifica

Materiale o nome chimico Jasplakinolide
CAS 102396-24-7
Formula molecolare C36H45BrN4O6
Quantità 100 μg
Sinonimo jasplakinolide
InChI Key GQWYWHOHRVVHAP-JFKHFEEVSA-N
SMILES CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C
IUPAC Name (4R,7R,10S,13S,15E,17R,19R)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone
Molecular Weight (g/mol) 709.682
PubChem CID 131843168
Peso formulazione 709.67
Percent Purity >97%
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