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  8. MI 2 (MALT1 inhibitor), Tocris Bioscience™

MI 2 (MALT1 inhibitor), Tocris Bioscience™

Codice prodotto. 30001668
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Quantità:
10 mg
50 mg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

MALT1 inhibitor

MALT1 inhibitor (IC50 = 5.84 μM). Binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF-κB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo.

Identificatori chimici

CAS 1047953-91-2
Formula molecolare C19H17Cl3N4O3
Molecular Weight (g/mol) 455.72
InChI Key TWJGQZBSEMDPQP-UHFFFAOYSA-N
Sinonimo mi 2 malt1 inhibitor, mi 2, 2-chloro-n-4-5-3,4-dichlorophenyl-3-2-methoxyethoxy-1h-1,2,4-triazol-1-yl phenyl acetamide, 2-chloro-n-4-5-3,4-dichlorophenyl-3-2-methoxyethoxy-1,2,4-triazol-1-yl phenyl acetamide, malt1 inhibitor mi-2, mi-2 malt1 inhibitor, mi 2 malt1 inhibitor; mi 2
PubChem CID 45942672
IUPAC Name 2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
SMILES COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl

Specifica

Materiale o nome chimico MI 2 (MALT1 inhibitor)
Quantità 50 mg
Peso formulazione 455.72
Percent Purity >98%
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