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Thermo Scientific Chemicals Mitomycin C, contains 2 mg Mitomycin C and 48 mg NaCl
Mitomycin C, CAS # 50-07-7, is a methylazirinopyrroloindoledione complex isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. It is a versatile and potent compound with antibiotic activity and may have potential therapeutic value in the treatment of cancer.
Marca: Thermo Scientific Chemicals 226940020
115.85 EUR valido fino al 2024-12-31
Usa il codice promo "21665" per avere il tuo prezzo promozionale.
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Descrizione
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
- Mitomycin C is a water soluble, blue-violet crystalline powder, unstable in light and acidic conditions, but may be stably stored at 2-8°c
- Bio-reduced mitomycin C generates oxygen radicals, alkylates DNA, and produces inter-strand DNA cross-links, thereby inhibiting DNA synthesis
Applications
- Mitomycin C is preferentially toxic to hypoxic cells that are resistant to cancer therapy, and is therefore used to study its potential therapeutic effect on advanced stages of cancer
- At high concentrations, mitomycin C inhibits RNA and protein synthesis and demonstrates strong antibiotic properties towards both Gram-positive and Gram-negative bacteria
Specifica
| Mitomycin C | |
| >360.0°C | |
| Ampoule | |
| MFCD00078109 | |
| 15, 6300 | |
| Solubility in water: soluble. Other solubilities: soluble in methanol, acetone, butyl acetate and, cyclohexanone;, slightly soluble in benzene, ccl4, diethyl ether;, practically insoluble in petroleum ether. | |
| CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N | |
| 5746 | |
| 334.32 | |
| Powder |
| 50-07-7, 7647-14-5 | |
| Blue-Violet | |
| C15H18N4O5 | |
| 2 mg | |
| mitomycin c, mitomycin, ametycine, mutamycin, ametycin, mitocin-c, mitomycinum, mytomycin, mytozytrex, mitomycin-c | |
| NWIBSHFKIJFRCO-WUDYKRTCSA-N | |
| 334.32 | |
| CHEBI:27504 | |
| ≥99% with regard to the non-formulated material |
Sicurezza e movimentazione
Identificativo prodotto
Avvertenza
Categoria di pericolo
Indicazioni di pericolo
Consigli di prudenza
- Mitomycin C
Avvertenza
- Attenzione
Categoria di pericolo
- Tossicità acuta Categoria 4
- cancerogenicità Categoria 2
Indicazioni di pericolo
- H351-Sospettato di provocare il cancro.
- H302-Nocivo se ingerito.
Consigli di prudenza
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P301+P312-IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI/medico/
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Titolo del prodotto
RUO – Research Use Only
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