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  6. N-Acetyl-D-mannosamine, 98%, Thermo Scientific Chemicals

N-Acetyl-D-mannosamine, 98%, Thermo Scientific Chemicals

Codice prodotto. 10527970
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Quantità:
1 g
5 g
Imballaggio:
Glass bottle
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

N-Acetyl-D-mannosamine (ManNAc), CAS # 7772-94-3, is a monosaccharide sialic acid precursor.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• N-Acetyl-D-mannosamine (ManNAc) is a precursor used to synthesize N-acetylneuraminic acid, the most common physiologic sialic acid present in humans and other mammals
• Sialic acids are terminal sugars on glycoconjugates that can modify biochemistry of glycoproteins and lipids, mediate cellular adhesion, and act as immune regulators
• Defects in sialic acid biosynthesis are associated with a number of pathologies
• Sialic acids are often found at increased expression levels on tumor cell surfaces
Applications
• As a sialic acid precursor, N-Acetyl-D-mannosamine can be used in many glycoengineering applications, such as modifying immune cell activity, imaging glycans, or blocking pathogen binding
• N-Acetyl-D-mannosamine hasbeen used in preclinical laboratory studies as a treatment for hereditary inclusion body myopathy, a progressive neuromuscular disease via increased sialylation of podocalyxin
• N-Acetyl-D-mannosamine has been used in laboratory studies to induce IgG sialylation and prevent obesity-induced hypertension in mice following high-fat diet
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 7772-94-3
Formula molecolare C8H17NO7
Molecular Weight (g/mol) 239.22
Numero MDL MFCD00149493,MFCD00046758,MFCD00149493,MFCD00069808
InChI Key VVQPUTSNIMAJPT-UHFFFAOYNA-N
Sinonimo n-acetylmannosamine
PubChem CID 11908605
IUPAC Name N-[(2R,3S,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
SMILES O.CC(=O)NC1C(O)OC(CO)C(O)C1O

Specifica

Materiale o nome chimico N-Acetyl-D-mannosamine
CAS min. % 97.5
CAS max % 100.0
Colore White
Spettro a infrarossi Authentic
Intervallo percentuale saggio 98%
Imballaggio Glass bottle
Quantità 5 g
Peso formulazione 221.21
Percent Purity ≥97.5%
Forma fisica Crystalline Powder
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Sicurezza e movimentazione

Identificativo prodotto
  • N-Acetyl-D-mannosamine

RUO – Research Use Only

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