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  6. NSFL1C Rabbit anti-Human, Mouse, Polyclonal, Proteintech

NSFL1C Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifica

Antigene NSFL1C
Concentrazione 0.29 mg/mL
Applicazioni Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Classificazione Polyclonal
Coniugato Unconjugated
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
16834874
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Proteintech
15620-1-AP-20UL 		20 μL
145.00€
20µL
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16824874
Visa dokument
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Proteintech
15620-1-AP-150UL 		150 μL
410.00€
150µL
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Beskrivning

Beskrivning

p47, also known as NSFL1C, UBX1, UBXD10 or UBXN2C, is a 370 amino acid protein that localizes to both the nucleus and the golgi apparatus (specifically to golgi stacks) and contains one SEP domain and one UBX domain. Functioning as part of a ternary complex with VCP (a protein involved in the heterotypic fusion of transport vesicles with their target membranes) and Syntaxin 5, p47 interacts with and reduces the ATPase activity of VCP and is required for the fragmentation of golgi stacks during mitosis and for subsequent reassembly of golgi stacks after mitosis. p47 is subject to phosphorylation during mitosis, which inhibits p47-golgi interaction and is, therefore, required for proper golgi stack formation and cisternal regrowth. Human p47 shares 89% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of p47 exist due to alternative splicing events.
Specifikationer

Specifikationer

NSFL1C
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse
Q9CZ44, Q9UNZ2
386649, 55968
NSFL1C Fusion Protein Ag8040
Primary
-20°C
NSFL1C
0.29 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
NSFL1 (p97) cofactor (p47), NSFL1 cofactor p47, NSFL1C, p47, p97 cofactor p47, UBX1, UBXD10, UBXN2C
Nsfl1c
IgG
Antigen Affinity Chromatography
Antibody
Filmer
SDS
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