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Invitrogen™ PIK3CB/PIK3R1 (p110 beta/p85 alpha) Recombinant Human Protein
PIK3CB/PIK3R1 (p110β/p85α) is a phosphoinositide-3-kinase (PI3K) comprised of a catalytic subunit, p110β, and a regulatory subunit, p85α, encoded by the PIK3CB and PIK3R1 genes respectively.
Marca: Invitrogen™ PV6456
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Descrizione
As with other members of the PI3K family, p110β has important regulatory roles in cellular processes including cell survival, proliferation, and differentiation. It affects growth factor signaling and survival by phosphorylating inositol lipids. PTEN-deficient cancer cells have been observed to depend on p110β signaling.
- Available in 3 convenient sizes
- Validated in our Adapta™ and Kinase Binding assays
- A full-length protein that can help advance your research when used in validated assays
Specifica
| NP_852664.1/NP_006210.1 | |
| 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | |
| 84.7kDa/123.7kDa | |
| Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. | |
| phosphatidylinositol-4/p110β/p85α/p110 beta/p85 alpha/5-bisphosphate 3-kinase | |
| Human | |
| His Tag |
| Kinase Assay, Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| PIK3CB, PIK3R1 | |
| 1 mg | |
| Full Length, Recombinant, Active | |
| PI3 Kinase | |
| Recombinant | |
| Baculovirus |
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