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Prednisone, 98%, Thermo Scientific Chemicals

Codice prodotto. 13458638
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Quantità:
5 g
25 g
Imballaggio:
Glass bottle
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Prednisone, 98%, CAS # 53-03-2, is a synthetic glucocorticoid with anti-inflammatory, immunomodulatory, antineoplastic, and adrenergic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities

• It shows antineoplastic and adrenergic activities against hormone-sensitive cancer cells

• This compound binds to its receptors and enters the nucleus activating specific nuclear receptors, resulting in an altered gene expression and inhibiting proinflammatory cytokine production

Applications

• Prednisone can reduce circulating lymphocytes, promote cell differentiation, and stimulate apoptosis in sensitive tumor cell lines

• It is considered a prodrug that is converted by the liver into prednisolone which is the active steroid compound

• It is also used in some studies to investigate the effects of daily administration of MIDD0301, on the animal and organs weights and hematological profile

TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 53-03-2
Formula molecolare C21H26O5
Molecular Weight (g/mol) 358.434
InChI Key XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Sinonimo prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin
PubChem CID 5865
ChEBI CHEBI:8382
IUPAC Name (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C

Specifica

Materiale o nome chimico Prednisone
Intervallo percentuale saggio 98%
Imballaggio Glass bottle
Quantità 5 g
Peso formulazione 358.43
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Identificativo prodotto
  • Prednisone
Avvertenza
  • Attenzione
Categoria di pericolo
  • Tossicità per la riproduzione Categoria 2
Indicazioni di pericolo
  • H361-Sospettato di nuocere alla fertilità o al feto.
Consigli di prudenza
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P202-Non manipolare prima di avere letto e compreso tutte le avvertenze.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.

RUO – Research Use Only

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