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RO-3, Tocris Bioscience™

Codice prodotto. 18095602
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Quantità:
10 mg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Selective P2X3 and P2X2/3 antagonist

Selective homomeric P2X3 and heteromeric P2X2/3 receptor antagonist (pIC50 values are 7.0 and 5.9 respectively) that exhibits no activity at P2X1, P2X2, P2X4, P2X5 and P2X7 receptors (IC50 > 10 μM). Attenuates nociceptive sensitivity in animal models of pain. Orally active and brain penetrant.

Specifica

Materiale o nome chimico RO-3
CAS 1026582-88-6
Formula molecolare C16H22N4O2
Quantità 10 mg
Sinonimo ro-3, ro3, 5-4,5-dimethoxy-2-methylethyl phenyl methyl-2,4-pyrimidinediamine, d0g8ni, 5-4,5-dimethoxy-2-propan-2-yl phenyl methyl pyrimidine-2,4-diamine
InChI Key PYNPWUIBJMVRIG-UHFFFAOYSA-N
SMILES CC(C)C1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC
IUPAC Name 5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine
Molecular Weight (g/mol) 302.378
PubChem CID 11289644
Peso formulazione 302.37
Percent Purity >98%
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