Invitrogen™ RSV M2 Polyclonal Antibody

Descrizione

PA1-23415 detects Respiratory Syncytial Virus M2 Protein in Virus samples.

The RSV (Respiratory Syncytial Virus) M2 gene encodes for two critical proteins, M2-1 and M2-2. The M2-1 protein is essential for viral transcription, acting as an elongation factor, ensuring the synthesis of full-length viral mRNAs. It associates non-covalently with the viral RNA-dependent RNA polymerase complex. Transcription regulation is influenced by the phosphorylation state of M2-1, mediated by cellular protein phosphatase 1 (PP1). In contrast, the M2-2 protein plays a significant role in regulating the balance between viral transcription and replication. These functions underscore the crucial roles of M2 gene products in the RSV lifecycle and their importance as potential targets for antiviral strategies.