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SF3A2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA560147
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Descrizione
Immunogen sequence: EVKKFVKIGR PGYKVTKQRD SEMGQQSLLF QIDYPEIAEG IMPRHRFMSA YEQRIEPPDR RWQYLLMAAE PYETIAFKVP SREIDKAEGK FWTHWNRETK QFFLQFHFKM EKP Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.Specifica
SF3A2 | |
Polyclonal | |
Unconjugated | |
SF3A2 | |
66kDa; AW047242; pre-mRNA splicing factor SF3A, subunit 2; PRP11; PRPF11; SAP 62; Sap62; Sf3a2; SF3a66; SFA66; spliceosomal protein gene 62; spliceosome associated protein 62; spliceosome-associated protein 62; Splicing factor 3A subunit 2; splicing factor 3a, subunit 2; splicing factor 3a, subunit 2, 66kD; splicing factor 3a, subunit 2, 66kDa | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8175 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry, Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q15428 | |
SF3A2 | |
Recombinant protein corresponding to Human SF3A2 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only