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  8. Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%

Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%

Codice prodotto. 11312727
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Quantità:
1 g
5 g
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Descrizione

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.

Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 298-93-1
Formula molecolare C18H16BrN5S
Molecular Weight (g/mol) 414.33
Numero MDL MFCD00011964,MFCD00066662
InChI Key AZKSAVLVSZKNRD-UHFFFAOYSA-M
Sinonimo thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i
PubChem CID 64965
ChEBI CHEBI:53233
IUPAC Name 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide
SMILES [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1

Specifica

Materiale o nome chimico Thiazolyl Blue tetrazolium bromide
Punto di fusione ∽195°C (decomposition)
Odore Odorless
Quantità 5 g
Beilstein 3825277
Sensibilità Air, light, and moisture sensitive
Informazioni di solubilità Soluble in water,ethanol,2-methoxyethanol and phosphate buffered saline.
Peso formulazione 414.33
Percent Purity 98%

Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • Thiazolyl Blue tetrazolium bromide
 Avvertenza
  • Attenzione
 Categoria di pericolo
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
  • Corrosione/irritazione della pelle Categoria 2
 Indicazioni di pericolo
  • H315-Provoca irritazione cutanea.
  • H319-Provoca grave irritazione oculare.
  • H335-Può irritare le vie respiratorie.
 Consigli di prudenza
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P405-Conservare sotto chiave.
  • P501-Smaltire il prodotto/recipiente in conformità con le disposizioni locali/regionali/nazionali/internazionali..

RUO – Research Use Only

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