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Thermo Scientific Chemicals 4-Epioxytetracycline, 'can be used as secondary standard'

Codice prodotto. 10389380
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Quantità:
100 mg
Imballaggio:
Glass bottle
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Descrizione

4-Epioxytetracycline, CAS # 14206-58-7, is one of the main oxytetracycline metabolites that show antibacterial activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 4-Epioxytetracycline is a metabolite of the oxytetracycline compound that displays antibacterial activity
  • It is the main degradation product derived from the oxytetracycline metabolization and has been detected in some biological samples
  • Its mechanism of action has been described to be related to the mitochondrial protein synthesis inhibition

Applications

  • In laboratory research it has been described that the treatment with 4-epioxytetracycline decreases the bacterial diversity of the intestinal microbiota and facilitates the proliferation of opportunistic pathogens in salmon
  • The use of 4-epioxytetracycline in animal models (wistar rats) resulted in a significant alteration of the gut microbiota and disorders in blood metabolomics
  • 4-Epioxytetracycline can be applied as a secondary reference standard during stability studies of oxytetracycline
  • 4-epioxytetracycline has been used in research studies to evaluate the degradation pathway and products of tetracyclines
TRUSTED_SUSTAINABILITY

Specifica

Materiale o nome chimico 4-Epioxytetracycline
Nota nome 97%
CAS 14206-58-7
CAS min. % 96.0
CAS max % 100.0
Punto di fusione 168.0°C
Colore Beige-Green to Brown
Spettro a infrarossi Authentic
Intervallo percentuale saggio 80% min. (as is,calculated)
Imballaggio Glass bottle
Formula molecolare C22H24N2O9
Numero MDL MFCD00062825
Quantità 100 mg
Indice di Merck 10, 6846
Rotazione specifica − 247.00
Sinonimo 4-epioxytetracyline, unii-73von8sry5, 4-epioxytetracycline, 73von8sry5, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide, hydroxy quatrimycin, oxytetracycline dihydrate specified impurity a ep, oxytetracycline hydrochloride specified impurity a ep, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 2-naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, 4r,4ar,5s,5ar,6s,12as
Informazioni di solubilità Solubility in water: 0.5g/L. Other solubilities: 3.6g/L methanol
InChI Key OWFJMIVZYSDULZ-DVJPNYBFSA-N
SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
IUPAC Name (4R,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Molecular Weight (g/mol) 460.43
PubChem CID 54678403
Peso formulazione 460.43
Percent Purity ≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC)
Forma fisica Powder
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Sicurezza e movimentazione

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Identificativo prodotto
  • 4-Epioxytetracycline
 Avvertenza
  • Attenzione
 Categoria di pericolo
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Tossicità per la riproduzione Categoria 2
 Indicazioni di pericolo
  • H361d-Sospettato di nuocere al feto.
  • H319-Provoca grave irritazione oculare.
 Consigli di prudenza
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.

RUO – Research Use Only

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