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BD Pharmingen™ IHC Zinc Fixative
An alternative to formalin fixation of tissue for paraffin embedded sections
159.00€ - 381.00€
Specifica
| Colore | Clear |
|---|---|
| Content And Storage | Room temperature |
| Product Type | Fixative |
| Da utilizzare con (applicazione) | Immunohistochemical staining |
| Forma | Liquid |
| Codice del prodotto | Marca | Diluizione | Quantità | Prezzo | Quantità e disponibilità | ||||
|---|---|---|---|---|---|---|---|---|---|
| Codice del prodotto | Marca | Diluizione | Quantità | Prezzo | Quantità e disponibilità | ||||
|
10400275
|
BD
550523 |
1 X | 1000mL |
159.00€
Pezzo |
Spedizione stimata: 22-01-2025
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|
15886838
|
BD
552658 |
10 X | 500mL |
381.00€
Pezzo |
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Descrizione
Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.
- Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
- Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases
There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.
Specifica
| Clear | |
| Fixative | |
| Liquid |
| Room temperature | |
| Immunohistochemical staining |