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BD Pharmingen™ IHC Zinc Fixative

An alternative to formalin fixation of tissue for paraffin embedded sections

159.00€ - 381.00€

Specifica

Colore Clear
Content And Storage Room temperature
Product Type Fixative
Da utilizzare con (applicazione) Immunohistochemical staining
Forma Liquid
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Prodotti 2
Codice del prodotto Marca Diluizione Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Diluizione Quantità Prezzo Quantità e disponibilità  
10400275
Vedere i documenti
BD
550523
1 X 1000mL
159.00€
Pezzo
Spedizione stimata: 04-02-2025
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15886838
Vedere i documenti
BD
552658
10 X 500mL
381.00€
Pezzo
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Descrizione

Descrizione

Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.

  • Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
  • Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases

There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.

Specifica

Specifica

Clear
Fixative
Liquid
Room temperature
Immunohistochemical staining
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