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Ceritinib, MedChemExpress

MedChemExpress Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency.

Marca:  Medchem Express HY-15656

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Codice prodotto. 16442807

  • 153.90€ / 50mg

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Descrizione

Descrizione

Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency.
Specifica

Specifica

Ceritinib
White
C28H36ClN5O3S
LDK378
CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3
558.14
Research
Cancer-Kinase/protease
1032900-25-6
Research
50 mg
DMSO : 5.6 mg/mL (10.03 mM; Need ultrasonic) ∣Ethanol : ≥ 3.33 mg/mL (5.97 mM)
558.14
97.21%
Solid
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