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Cycloheximide, Tocris Bioscience™
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Quantità:
100 mg
Descrizione
Selective inhibitor of eukaryotic (over prokaryotic) protein synthesis, blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T cells. Competitively inhibits the PPIase hFKBP12 (Ki = 3.4 μM). Also inhibits ferroptosis. Antifungal antibiotic. Exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.16 μM).
Specifica
Specifica
Materiale o nome chimico | Cycloheximide |
CAS | 66-81-9 |
Formula molecolare | C15H23NO4 |
Numero MDL | MFCD00082346 |
Quantità | 100 mg |
Sinonimo | cycloheximide, actidione, cycloheximide, naramycin a, kaken, actidion, actidone, hizarocin, naramycin, neocycloheximide |
InChI Key | YPHMISFOHDHNIV-QTEFRXOUNA-N |
SMILES | [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1 |
IUPAC Name | 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione |
Molecular Weight (g/mol) | 281.35 |
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