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Kanamycin monosulfate, Cell Culture Grade, Thermo Scientific Chemicals
Descrizione
Kanamycin monosulfate, is used as an aminoglycoside antibiotic. Kanamycin can be used as a selection agent in several types of isolation media.Kanamycin sulfate from Streptomyces kanamyceticus has been used in tissue culture media. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100mg/mL.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Kanamycin monosulfate is the sulfate salt form of kanamycin A
• It was isolated from Streptomyces kanamyceticus
• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence
Application
• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
• This compound is also involved in translating prokaryotic ribosomes
• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated
Literature References
Patel, K. N.; Limgavkar, R. S.; Raval, H. G.; Patel, K. G.; Gandhi, T. R. High-Performance Liquid Chromatographic Determination of Cefalexin Monohydrate and Kanamycin Monosulfate with Precolumn Derivatization. J. Liq. Chromatogr. Related Technol. 2015, 38 (6), 716-721.
Chi, Z.; Rong, Y. J.; Li, Y.; Tang, M. J.; Chi, Z. M. Biosurfactins production by Bacillus amyloliquefaciens R3 and their antibacterial activity against multi-drug resistant pathogenic E. coli. Bioprocess. Biosyst. Eng. 2015, 38 (5), 853-861.
Specifica
Specifica
| Materiale o nome chimico | Kanamycin monosulfate |
| Tipo | Kanamycin Monosulfate |
| Forma fisica | Powder |
| Colore | White |
| Quantità | 5 g |
| Indice di Merck | 14,5281 |
| Informazioni di solubilità | Soluble in water at 10mg/ml |
| Peso formulazione | 582.58 |
| Grado | Cell Culture |
Sicurezza e movimentazione
- Kanamycin monosulfate, Cell Culture Grade
- Pericolo
- Tossicità per la riproduzione Categoria 1B
- Sensibilizzante delle vie respiratorie Categoria 1
- Sensibilizzazione della pelle Categoria 1
- H317-Può provocare una reazione allergica cutanea.
- H334-Può provocare sintomi allergici o asmatici o difficoltà respiratorie se inalato.
- H360FD-Può nuocere alla fertilità. Può nuocere al feto.
- P201-Procurarsi istruzioni specifiche prima dell'uso.
- P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
- P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
- P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
- P342+P311-In caso di sintomi respiratori: contattare un CENTRO ANTIVELENI/un medico/ .
- MIXTURE LIST-Contiene: Kanamycin sulphate
RUO – Research Use Only
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