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Tocris™ VCP 171
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
274.29€ - 1058.29€
Specifica
| Materiale o nome chimico | [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone |
|---|---|
| CAS | 1018830-99-3 |
| Bersaglio | Adenosine A1 Receptor Modulators |
| Formula molecolare | C18H12F3NOS |
| Purezza | 0.98 |
| Product Code | Brand | Quantità | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantità | Price | Quantity & Availability | |||||
|
18779916
|
Tocris™
6261/10 |
10 mg |
274.29€
10mg |
Spedizione stimata: 05-08-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
|
18759886
|
Tocris™
6261/50 |
50 mg |
1058.29€
50mg |
Spedizione stimata: 05-08-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Description
VCP 171 is an adenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5.65, binding cooperativity with NECA 0.68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor-mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve-injury model of neuropathic pain.Specifications
| [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone | |
| Adenosine A1 Receptor Modulators | |
| 0.98 |
| 1018830-99-3 | |
| C18H12F3NOS |