GABRQ Polyclonal Antibody, Invitrogen™

Descrizione

Immunogen sequence: NYLFYSRGPR RQPRRHRRPR RVIARYRYQQ VVVGNVQDGL INVEDGVSSL PITPAQAPLA SPESLGSLTS TSEQAQLATS ESLSPLTSLS GQAPLATGES LSDLPSTSEQ ARHSYGVRFN GFQADDSIIP TEIRNRVEAH GHGVTHDHED SNESLSSDER HGHGPSGKPM LHHGEKGVQE AGWDLDDNND KSDCLAIKEQ FKCDTNSTWG LNDDELMAHG QEKDSSSESE DSCPPSPGCS FTEGFSFDLF N; Positive Samples: Jurkat; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).