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Tyrosinase Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ Tyrosinase Ab-1, Mouse Monoclonal Antibody.
178.50€ - 1095.00€
Specifica
Antigene | Tyrosinase Ab-1 |
---|---|
Clone | T311 |
Applicazioni | Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
Classificazione | Monoclonal |
Specie ospite | Mouse |
Codice del prodotto | Marca | Forma | Coniugato | Quantità | Prezzo | Quantità e disponibilità | |||
---|---|---|---|---|---|---|---|---|---|
Codice del prodotto | Marca | Forma | Coniugato | Quantità | Prezzo | Quantità e disponibilità | |||
12612337
|
Epredia
MS-800-B0 |
Concentrated | Biotin | 100 μL | N/A | ||||
12622337
|
Epredia
MS-800-B1 |
Concentrated | Biotin | 500 μL |
751.00€
500µL |
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12602337
|
Epredia
MS-800-B |
Concentrated | Biotin | 1 mL | N/A | ||||
12642337
|
Epredia
MS-800-P0 |
Concentrated | Unconjugated | 100 μL | N/A | ||||
12662337
|
Epredia
MS-800-P1ABX |
Concentrated | Unconjugated | 100 μL | N/A | ||||
12672337
|
Epredia
MS-800-PABX |
Concentrated | Unconjugated | 200 μL | N/A | ||||
12652337
|
Epredia
MS-800-P1 |
Concentrated | Unconjugated | 500 μL | N/A | ||||
12632337
|
Epredia
MS-800-P |
Concentrated | Unconjugated | 1 mL |
1040.00€
1mL |
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12602347
|
Epredia
MS-800-R7 |
Prediluted | Unconjugated | 7 mL | N/A | ||||
12612347
|
Epredia
MS-800-RQ |
Ready-to-Use | Unconjugated | 12 mL |
537.00€
12mL |
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Descrizione
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.Host Species: Mouse
Clone: T311
Isotype: IgG2a
Species Reactivity: Human, Dog and Cat. Weakly cross-reacts with Mouse. Others not known.
Epitope: aa 1-433
Immunogen: Recombinant tyrosinase protein
Molecular Weight: 70-80kDa
Positive Control: Melanoma cell lines and Melanoma
Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Staining of melanomas with Ab-1 showed tyrosinase in melanotic as well as amelanotic variants. Ab-1 is a useful marker for melanocytes and melanomas. Occasionally a minor band at 55kDa is also detected in Western Blotting
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunocytology
Specifica
Tyrosinase Ab-1 | |
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
Mouse | |
Cancer and Tumor Biology | |
Primary |
T311 | |
Monoclonal | |
IVD | |
Recombinant tyrosinase protein |
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