Thermo Scientific™ IMAGEN™ Respiratory Syncytial Virus Kit (RSV) using Direct Immunofluorescence Assay

Descrizione

Rapidly detect the Respiratory Syncytial Virus (RSV) in clinical samples with Thermo Scientific™ IMAGEN™ Respiratory Syncytial Virus Kit. This direct immunofluorescence assay utilizes three monoclonal antibodies in order to detect specific structural proteins expressed in all strains of human Respiratory Syncytial Virus

RSV is the major cause of lower respiratory tract diseases in infants and young children causing seasonal epidemics of respiratory illness each year ^{1, 2}.

Use IMAGEN Respiratory Syncytial Virus Kit as a rapid, sensitive and specific method for direct detection of RSV in clinical samples such as nasopharyngeal aspirates.

• Rapid results- within little over 30 minutes of receiving test sample or culture
• Simple- ready-to-use reagents plus all IMAGEN assays follow the same basic methodology
• Excellent sensitivity and specificity- high quality, well-characterized antibodies used in the assay provide excellent sensitivity and specificity
• Easy-to-read results
• Long Shelf Life- typically 24 months

RSV is an enveloped, spherical, RNA virus of the family paramyxoviridae and is classified in the genus Pneumovirus. This genus has four members: human RSV, bovine RSV, pneumonia virus of mice and turkey rhinotracheitis virus^{3, 4}. RSV is spread by virus-laden droplets of respiratory secretions from infected individuals. Infection may manifest as a variety of symptoms, ranging from rhinitis to pneumonia, which are influenced by factors such as the age, sex and socio-economic background of infected individuals.⁵

The laboratory diagnosis of RSV plays an important role in patient management and assists in the control of outbreaks^{6, 7, 8,9, 10}. Methods commonly employed for laboratory diagnosis of RSV infection include direct detection of virus or viral proteins in clinical samples such as nasopharyngeal aspirates and isolation of viable virus in cell culture monolayers inoculated with respiratory secretions^{11, 12}

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