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Thermo Scientific™ Cocktail inibitore della fosfatasi Halt™
Stabilize serine, threonine and tyrosine phosphorylation of proteins in cells and tissues with this cocktail of phosphatase inhibitors.
Marca: Thermo Scientific™ 78420
162.40 EUR valido fino al 2024-09-27
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Descrizione
Preserve phosphorylation of proteins in cells and tissues with Thermo Scientific™ Halt Phosphatase Inhibitor Cocktail.
- Halt Phosphatase Inhibitor Cocktail protects phosphoproteins from serine/threonine phosphatases, as well as protein tyrosine phosphatases (PTPs) during cell lysis
- The cocktail contains a mixture of four inhibitors of broad specificity including sodium fluoride, sodium orthovanadate, sodium pyrophosphate, and beta-glycerophosphate
- Conveniently packaged in a 100X format, the cocktail is stable at 4°C and is suitable for use with any cell or tissue extract
- The cocktail preserves protein phosphorylation in immunoprecipitation and kinase assays
- Phosphorylation and dephosphorylation comprise a molecular on/off switch that regulates many key biological pathways within the cell including signal transduction, cell division, and apoptosis
- To effectively study phosphorylation activation states, one must inactivate phosphatases to prevent their uncontrolled activity upon cell lysis
Additional Features
- Devoid of protease inhibitors – To protect against both proteases and phosphatases, use Halt Protease and Phosphatase Inhibitor Cocktail (78420)
- Dialyzable – Either dialyze or desalt sample to effectively remove inhibitors from cell extracts before performing procedures that are discovered to be incompatible with cocktail components
- Supplied as a 100X concentrate – effective when used at a final concentration of 1X; however, samples that contain particularly high levels of phosphatase activity may require a final concentration of 2-3X
- Compatibility – compatible with most detergent-based cell lysis reagents, including all Thermo Scientific Pierce Cell Lysis Solutions
- All-in-one format – inhibits both serine-threonine phosphatases and protein tyrosine phosphatases
- Compatible with popular protein assays – works with standard protein assays, including BCA and coomassie (Bradford) assays
- Convenient storage – refrigerator storage (2 to 8°C) saves valuable space in the freezer and allows for immediate use
![TRUSTED_SUSTAINABILITY](/content/dam/fishersci/glyphs/Sustain_Badge.png)
Specifica
Phosphatase Inhibitor Cocktail | |
Liquid | |
Phosphatase Inhibitor | |
1 ml |
Upon receipt store product at 4°C. Do not freeze. | |
Halt™ | |
Phosphatase Inhibitor |
Sicurezza e movimentazione
Identificativo prodotto
Avvertenza
Categoria di pericolo
Indicazioni di pericolo
Consigli di prudenza
Informazioni supplementari
- Halt Phosphatase Inhibitor Cocktail
Avvertenza
- Attenzione
Categoria di pericolo
- Tossicità acuta Categoria 4
Indicazioni di pericolo
- H302-Nocivo se ingerito.
Consigli di prudenza
- P270-Non mangiare, né bere, né fumare durante l'uso.
- P264-Lavare accuratamente dopo l'uso.
- P301+P312-IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI/medico/
- P330-Sciacquare la bocca.
- P501-Smaltire il prodotto/recipiente in .
Informazioni supplementari
- MIXTURE LIST-Contiene: sodium fluoride, trisodium tetraoxovanadate
For Research Use Only. Not for use in diagnostic procedures.