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UNC13B Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA590699
338.68 EUR valido fino al 2025-03-21
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Allerta:
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Descrizione
Immunogen sequence: MSLLCVRVKR AKFQGSPDKF NTYVTLKVQN VKSTTVAVRG DQPSWEQDFM FEISRLDLGL SVEVWNKGLI WDTMVGTVWI ALKTIRQSDE EGPGEWSTLE AETLMKDDEI CGTRNPTPHK ILLDTRFELP FDIPEEEARY WTYKWEQINA LGADNEYSSQ EESQRKPLPT AAAQCSFEDP DSAVDDRDSD YRSETSNSFP PPYHTASQPN ASVHQFPVPV RSPQQLLLQG SSRDSCNDSM QSYDLDYPER RAISPTSSSR YGSSCNVSQG SSQLSELDQY HEQDDDHRET DSIHSCHSSH SLSRDGQAGF GEQEKPLEVT GQAEKEAACE PKEMKEDATT HPPPDLVLQK; Positive Samples: 293T, LO2; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Membrane, Peripheral membrane protein, synapse
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.
Specifica
UNC13B | |
Polyclonal | |
Unconjugated | |
UNC13B | |
homolog of rat Munc13 (diacylglycerol-binding), munc13, Munc13-1, Munc13-2, protein unc-13 homolog B, UNC13, unc13 homolog 1, UNC-13 homolog 1, unc-13 homolog A, unc-13 homolog B, unc-13 homolog B (C. elegans), Unc13a, Unc13b, Unc13h1, Unc13h2 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
10497, 22249 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
0.46 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3 | |
O14795, Q9Z1N9 | |
UNC13B | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human UNC13B (NP_0063683) | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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